Question 1

A cluster of functionally-related genes that are regulated together and encoded into a single mRNA molecule is called a(n)

Accepted Answer

A)  operon.
B)  repressor.
C)  promoter.
D)  operator.
E)  CAP.

Question 2

Elucidation of the histone code might

Accepted Answer

A)  allow us to turn specific genes on or off.
B)  allow the determination of nucleosome composition.
C)  lead to chromatin remodeling.
D)  allow us to control translation.

Question 3

The maintenance of a constant environment in a cell is called ________.

Accepted Answer

A)  active transport
B)  homeostasis
C)  gene expression
D)  translation

Question 4

Enhancers are the binding sites for the

Accepted Answer

A)  promoters of DNA synthesis.
B)  suppressor factors.
C)  coactivation factors.
D)  mediator factors.
E)  specific transcription factors.

Question 5

You are studying regulation of a prokaryotic operon.Experiments show that expression of the operon is increased when levels of biosynthetic product from that pathway are low.Based on this information,what is a likely mode of regulation?

Accepted Answer

A)  The product binds a repressor,allowing it to bind the operator.
B)  The product binds an activator,helping RNA polymerase to bind the promoter.
C)  The product binds a repressor,preventing it from binding the operator.
D)  The product binds to the biosynthetic enzymes,blocking them directly.

Question 6

Histones that are tightly wound by DNA and are the basic unit of chromatin are called

Accepted Answer

A)  operons.
B)  nucleosomes.
C)  protein clusters.
D)  repressor genes.
E)  facilitators sites.

Question 7

Certain proteins can bind to specific DNA regulatory sequences by entering

Accepted Answer

A)  the major groove of the DNA and reading the nucleotide base pairs.
B)  the minor groove of the DNA and reading the nucleotide base pairs.
C)  the major groove of RNA and reading the nucleotide base pairs.
D)  DNA's major groove by using DNA polymerase and reading the nucleotide base pairs.
E)  DNA's minor groove by using DNA polymerase and reading the nucleotide base pairs.

Question 8

Eukaryotic cell mRNA transcripts can remain in the cell for hours because they are

Accepted Answer

A)  stable.
B)  long.
C)  isolated.
D)  analogous.

Question 9

The proteins necessary for the use of lactose in E.coli are collectively called the

Accepted Answer

A)  lac regulator.
B)  lac suppressor.
C)  lac operon.
D)  lac promoter.
E)  lac transcriptional operator.

Question 10

One of the DNA-binding motifs in many eukaryotic organisms that contains a nearly identical sequence of 60 amino acids is known as the

Accepted Answer

A)  nonhelical zipper.
B)  leucine zipper.
C)  zinc finger.
D)  homeodomain.
E)  helix-turn-helix.

Question 11

If you were given a bacterial strain with a mutation in the promoter region of the trp operon the most likely effect would be

Accepted Answer

A)  interference with RNA polymerase binding.
B)  to block the repressor from binding.
C)  derepression of the trp operon.
D)  enabling the trp operon to be expressed in the absence of tryptophan.
E)  lack of expression of just the first gene in the operon.

Question 12

In vertebrates,DNA methylation - the addition of a methyl group to DNA nucleotides - ensures that

Accepted Answer

A)  the gene functions without interruption.
B)  no errors will be made during transcription.
C)  the nucleosome will quickly form,which assists in mRNA formation.
D)  once that gene is transcribed,the mRNA is saved and used over and over again.
E)  once a gene is turned off,it will remain off.

Question 13

A protein that initiates gene transcription and allows for non-glucose molecules to be used is

Accepted Answer

A)  operon.
B)  repressor.
C)  promoter.
D)  operator.
E)  CAP.

Question 14

Through control of gene expression,a bacterial cell responds to changing ________ conditions.

Accepted Answer

A)  internal
B)  protein
C)  environmental
D)  genetic

Question 15

A site at the 5' end of a gene where RNA polymerase attaches to initiate transcription is called a(n)

Accepted Answer

A)  operon.
B)  repressor.
C)  promoter.
D)  operator.
E)  CAP.

Question 16

You lead a research team challenged with the task of creating a regulatory protein able to shut off transcription of a particular gene.You focus your design around a binding site called an operator that is associated with the promotor.The physical location of the operator most likely to affect transcription would be

Accepted Answer

A)  upstream of the gene promoter.
B)  downstream of the gene promoter.
C)  internal to the gene itself.
D)  internal to the gene promoter.

Question 17

Your research project involves the characterization of a recently identified transcription factor.As part of your project,you want to determine if this transcription factor binds directly to any of the general transcription factors.Unfortunately,you are having trouble expressing the full-length protein.What approach may help achieve your research goal?

Accepted Answer

A)  You must find a way to express the full-length protein,since transcription factor functions do not lie in separate domains.
B)  Identify the RNA that mediates the protein-protein binding.
C)  Express and purify only the DNA-binding domain,and test for binding.
D)  Express and purify only the activation domain,and test for binding.

Question 18

Although the specific mechanism of RNA interference has not been fully defined,it involves

Accepted Answer

A)  double stranded RNA interference with mRNA.
B)  double stranded RNA interference with DNA.
C)  double stranded DNA interference with mRNA.
D)  double stranded mRNA interference with DNA.

Question 19

You have been asked to design a synthetic DNA motif,able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the

Accepted Answer

A)  minor groove of the DNA double helix.
B)  major groove of the DNA double helix.
C)  phosphate backbone of the DNA double helix.
D)  sugar backbone of the DNA double helix.
E)  available hydrogen-bonds of bases in single-stranded DNA.

Question 20

A defining characteristic of eukaryotic organisms is that they

Accepted Answer

A)  have their transcription occurring in the cytoplasm and translation in the nucleus.
B)  have their transcription occurring in the nucleus and translation in the cytoplasm.
C)  have only operons to assist in gene expression.
D)  carry out protein synthesis only in the presence of the cAMP molecule.
E)  use the leucine zipper primarily for the production of the amino acid tryptophan.

Exam 16: Control of Gene Expression

A cluster of functionally-related genes that are regulated together and encoded into a single mRNA molecule is called a(n)

Correct Answer
verified

Although the specific mechanism of RNA interference has not been fully defined,it involves

Correct Answer
verified

The maintenance of a constant environment in a cell is called ________.

Correct Answer
verified

You have been asked to design a synthetic DNA motif,able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the

Correct Answer
verified

Correct Answer
verified

In vertebrates,DNA methylation - the addition of a methyl group to DNA nucleotides - ensures that

Correct Answer
verified

Through control of gene expression,a bacterial cell responds to changing ________ conditions.

Correct Answer
verified

The proteins necessary for the use of lactose in E.coli are collectively called the

Correct Answer
verified

Elucidation of the histone code might

Correct Answer
verified

Certain proteins can bind to specific DNA regulatory sequences by entering

Correct Answer
verified

Enhancers are the binding sites for the

Correct Answer
verified

You are studying regulation of a prokaryotic operon.Experiments show that expression of the operon is increased when levels of biosynthetic product from that pathway are low.Based on this information,what is a likely mode of regulation?

Correct Answer
verified

Correct Answer
verified

A site at the 5' end of a gene where RNA polymerase attaches to initiate transcription is called a(n)

Correct Answer
verified

A protein that initiates gene transcription and allows for non-glucose molecules to be used is

Correct Answer
verified

Eukaryotic cell mRNA transcripts can remain in the cell for hours because they are

Correct Answer
verified

If you were given a bacterial strain with a mutation in the promoter region of the trp operon the most likely effect would be

Correct Answer
verified

One of the DNA-binding motifs in many eukaryotic organisms that contains a nearly identical sequence of 60 amino acids is known as the

Correct Answer
verified

A defining characteristic of eukaryotic organisms is that they

Correct Answer
verified

Histones that are tightly wound by DNA and are the basic unit of chromatin are called

Correct Answer
verified

Exam 16: Control of Gene Expression

A cluster of functionally-related genes that are regulated together and encoded into a single mRNA molecule is called a(n)

Correct AnswerverifiedShow Answer

Although the specific mechanism of RNA interference has not been fully defined,it involves

Correct AnswerverifiedShow Answer

The maintenance of a constant environment in a cell is called ________.

Correct AnswerverifiedShow Answer

You have been asked to design a synthetic DNA motif,able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

In vertebrates,DNA methylation - the addition of a methyl group to DNA nucleotides - ensures that

Correct AnswerverifiedShow Answer

Through control of gene expression,a bacterial cell responds to changing ________ conditions.

Correct AnswerverifiedShow Answer

The proteins necessary for the use of lactose in E.coli are collectively called the

Correct AnswerverifiedShow Answer

Elucidation of the histone code might

Correct AnswerverifiedShow Answer

Certain proteins can bind to specific DNA regulatory sequences by entering

Correct AnswerverifiedShow Answer

Enhancers are the binding sites for the

Correct AnswerverifiedShow Answer

You are studying regulation of a prokaryotic operon.Experiments show that expression of the operon is increased when levels of biosynthetic product from that pathway are low.Based on this information,what is a likely mode of regulation?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

A site at the 5' end of a gene where RNA polymerase attaches to initiate transcription is called a(n)

Correct AnswerverifiedShow Answer

A protein that initiates gene transcription and allows for non-glucose molecules to be used is

Correct AnswerverifiedShow Answer

Eukaryotic cell mRNA transcripts can remain in the cell for hours because they are

Correct AnswerverifiedShow Answer

If you were given a bacterial strain with a mutation in the promoter region of the trp operon the most likely effect would be

Correct AnswerverifiedShow Answer

One of the DNA-binding motifs in many eukaryotic organisms that contains a nearly identical sequence of 60 amino acids is known as the

Correct AnswerverifiedShow Answer

A defining characteristic of eukaryotic organisms is that they

Correct AnswerverifiedShow Answer

Histones that are tightly wound by DNA and are the basic unit of chromatin are called

Correct AnswerverifiedShow Answer

Correct Answer
verified

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