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Exam 9: The Cell Cycle

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Question 1

Multiple Choice

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Besides the ability of some cancer cells to divide uncontrollably,what else might logically result in formation of a tumor?

A) enhanced anchorage dependence
B) changes in the order of cell cycle stages
C) lack of appropriate cell death
D) inability to form spindles

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Question 2

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The beginning of anaphase is indicated by which of the following events?

A) loss of kinetochores from sister chromatids
B) enzymatic cleavage of cohesin
C) joining of the sister chromatids to each other by cohesin
D) polymerization of spindle microtubules

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Question 3

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Progression through the M phase checkpoint is stimulated by a complex that does which of the following things?

Somatic cells in elephants have 56 chromosomes.How many chromosomes would be carried by the gametes produced by elephants?

The drug cytochalasin B blocks the function of actin.Which of the following aspects of the animal cell cycle would be most disrupted by cytochalasin B?

Where are the motor proteins that move chromosomes toward the poles of the mitotic spindle located?

Researchers established a number of cultured cell lines derived from different tumors.How might they determine which ones are malignant?

Most animal cells exhibit anchorage dependence,which means that in order to divide,

The unlettered circle at the top of the figure above shows a diploid nucleus with four chromosomes that have not yet replicated.There are two pairs of homologous chromosomes,one long and the other short.One haploid set is black,and the other is gray.The circles labeled A-E show various combinations of these chromosomes.What is the correct chromosomal condition for a nucleus at prophase of mitosis?

Humans produce skin cells by mitosis and gametes by meiosis.Which of the following statements about the nuclei of skin cells is correct?

Taxol is an anticancer drug extracted from the Pacific yew tree that binds to microtubules and prevents their depolymerization.Which phase of mitosis or cell division would be inhibited by treatment with Taxol?

Researchers studying a new cultured cell line observed that the cells did not exhibit either density-dependent inhibition or anchorage dependence.What could they conclude right away?

For a chemotherapeutic drug to be useful for treating cancer cells,which of the following characteristics is most desirable?

In the cells of some organisms,mitosis occurs without cytokinesis.This will result in

-In the figure above,which numbered segment(s) of the cycle represent G₁?

A group of cells is assayed for DNA content immediately before beginning mitosis and is found to have an average of 16 picograms of DNA per nucleus.How many picograms of DNA would be found in a cell nucleus following completion of mitosis and cytokinesis?

A particular cell has half as much DNA as some other cells in a mitotically active tissue.The cell in question is most likely in

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus.The measured DNA levels ranged from 3 to 6 picograms per nucleus.In which stage of the cell cycle would the nucleus contain 6 picograms of DNA?

Movement of the chromosomes during anaphase would be most affected by a drug that prevents which of the following processes?

What is a cleavage furrow?