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Which of the following statements about staphylococcal enterotoxin is FALSE?


A) It is a superantigen.
B) It is produced by Staphylococcus aureus growing in the host使s intestines.
C) It causes vomiting.
D) It causes diarrhea.
E) It is an exotoxin.

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B

The Limulus amoebocyte assay is used to detect minute amounts of endotoxin in drugs and medical devices.

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All of the following contribute to a pathogen使s invasiveness EXCEPT


A) capsules.
B) toxins.
C) hyaluronidase.
D) coagulases.
E) cell wall components.

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All of the following bacteria release endotoxin EXCEPT


A) Proteus vulgaris.
B) Clostridium botulinum.
C) Salmonella typhi.
D) Neisseria meningitidis.
E) Haemophilus influenzae.

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Which of the following is NOT a cytopathic effect of viruses?


A) host cells fusing to form multinucleated syncytia
B) inclusion bodies forming in the cytoplasm or nucleus
C) toxin production
D) increased cell growth
E) cell death

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Which of the following mechanisms is used by gram -negative bacteria to cross the blood-brain barrier?


A) producing toxins
B) inducing endocytosis
C) producing fimbriae
D) antigenic variation
E) inducing TNF

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Compare and contrast endotoxins and exotoxins. Why are exotoxins more potent than endotoxins?

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Endotoxins and exotoxins are both types ...

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In general, the LD50 for exotoxins is much greater than the LD50 for endotoxins.

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Cytopathic effects, such as inclusion bodies and syncytium formation, are the visible signs of viral infections.

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Antibiotics can kill gram-negative bacteria, but symptoms of fever and low blood pressure can persist. Why?

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Antibiotics can effectively kill gram-ne...

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Endotoxins are


A) A-B toxins.
B) associated with gram-positive bacteria.
C) part of the gram-negative cell wall.
D) excreted from the cell.
E) molecules that bind nerve cells.

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Injectable drugs are tested for endotoxins by


A) culturing bacteria.
B) the Limulus amoebocyte lysate test.
C) filtering out the cells.
D) looking for turbidity.
E) counting the viable bacteria.

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Which of the following statements about M protein is FALSE?


A) It is found on Streptococcus pyogenes.
B) It is heat- and acid-resistant.
C) It is a protein.
D) It is found on fimbriae.
E) It is readily digested by phagocytes.

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All of the following are used by bacteria to attach to host cells EXCEPT


A) A-B toxins.
B) M protein.
C) ligands.
D) capsules.
E) fimbriae.

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The ability of some microbes, such as Trypanosoma or Giardia to alter their surface molecules and evade destruction by the host使s antibodies is called


A) cytocidal effect.
B) antigenic variation.
C) virulence.
D) lysogenic conversion.
E) cytopathic effect.

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All of the following are methods of avoiding host antibodies EXCEPT


A) membrane-disrupting toxins.
B) antigenic changes.
C) inducing endocytosis.
D) IgA proteases.
E) invasins.

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A

Ergot and aflatoxin are toxins sometimes found in grains contaminated with fungi.

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Which of the following does NOT contribute to the symptoms of a fungal disease?


A) capsules
B) metabolic products
C) cell walls
D) allergic response of the host
E) toxins

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Nonpathogenic Vibrio cholerae can acquire the cholera toxin gene by


A) infecting a pathogenic Vibrio cholerae.
B) transduction.
C) transformation.
D) conjugation.
E) phagocytosis.

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B

Cytopathic effects are changes in host cells due to


A) viral infections.
B) helminthic infections.
C) protozoan infections.
D) fungal infections.
E) bacterial infections.

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