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All mature polypeptides contain a methionine at the N-terminus.

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Frequently, the start codon for the functional protein is not at the 5' end of the mRNA. In fact, there are often several codons 5' of the start codon in an edited mRNA prior to translation. What is the purpose of these codons in a eukaryotic system?


A) Ribosomal binding sites
B) Act as a promoter
C) Serve as sorting or traffic signals for the ribosome
D) Sites of spliceosome activity

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The one-gene, one-enzyme hypothesis was first proposed by Beadle and Tatum.

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The first person to suggest that a connection exists between the function of a gene and the production of an enzyme was Archibald Garrod.

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True

Where does mRNA/tRNA codon-anticodon recognition take place?


A) 30S
B) 40S
C) 50S
D) The surface between the two ribosomal subunits

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Which of the following codons is not degenerate to CUU?


A) CUC
B) UUG
C) CUA
D) AUU
E) UUA

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Which of the following is true according to the adaptor hypothesis?


A) The anticodon and amino acid have no relationship
B) A given tRNA can carry any of the twenty amino acids
C) tRNA binds to mRNA at the ribosome
D) An amino acid recognizes the codon in mRNA

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The peptidyltransferase complex is a component of which of the following?


A) DNA
B) tRNA
C) The ribosome
D) The functional protein
E) mRNA

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Where are the ribosomal subunits assembled?


A) Nucleus
B) Nucleoid
C) Nucleolus
D) Nuclear envelope

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RF1 and RF2 are active during .


A) Initiation
B) Elongation
C) Termination
D) Cotranslational import

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The C-terminal of a polypeptide always contains which of the following?


A) A stop codon
B) A carboxyl group
C) An amino group
D) Carbon dioxide
E) None of the answers are correct

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The anticodon on the mRNA recognizes the codon on the tRNA. FALSE

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The Shine-Dalgarno sequence is found in eukaryotic cells.

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False

How many polypeptides are coded for by the following mRNA: 5'GCCACCAUGGGCCAAUUACGAAGGUUUUGCUGACCAGGUCAA3'


A) 7
B) 8
C) 10
D) 13

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a-helices and b-sheets are examples of what level of protein structure?


A) Primary structure
B) Secondary structure
C) Tertiary structure
D) Quanternary structure

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Proteins that are composed of two or more subunits or polypeptides are said the have quanternary structure.

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The wobble base is usually associated with the second base of a codon.

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What is the modern theory of genetics?


A) One gene-one enzyme
B) One gene-one polypeptide
C) One gene-various number of enzymes
D) No relationship can be determined between genes and proteins

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The genetic code is universal in nuclear DNA from bacteria to mammals.

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Raney nickel converts cysteine to what?


A) Glycine
B) Asparagine
C) Alanine
D) Serine

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C

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