Question 1

Which of the following is your "C-value"?

Accepted Answer

A)   RNA size
B)   genome size
C)   chromosome size
D)   DNA size

Question 2

Match the following techniques with the descriptions listed below.
-used to compare the gene expression patterns of identical cells under different conditions

Accepted Answer

A)  whole-genome shotgun sequencing
B)  Illumina/Solexa sequencing
C)  Sanger sequencing
D)  DNA microarray analysis
E)  gene knockoutF) gene knockdown

Question 3

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below.
-genomics

Accepted Answer

A)  DNA
B)  mRNA/cDNA
C)  protein

Question 4

Which of these statements best describes the human genome?

Accepted Answer

A)   There are about 12 000 genes that do not encode proteins.
B)   Each gene averages 30 regulatory sequences for expression.
C)   There are no pseudogenes.
D)   There are, on average, 10 exons per gene.

Question 5

Which of the following is NOT a model organism whose genomes were sequenced as part of the original Human Genome Project?

Accepted Answer

A)   Mus musculus (mouse) 
B)   Escherichia coli (bacteria) 
C)   Drosophila melanogaster (fruit fly) 
D)   Danio rerio (zebrafish)

Question 6

Which of the following is NOT considered a source of evolving genes?

Accepted Answer

A)   a gene duplication from unequal crossing-over
B)   a gene duplication from replicating transposable elements
C)   a gene duplication from crossing-over
D)   an exon shuffling

Question 7

What are the relationships among the following types of organisms with respect to genome size: viruses, bacteria, archaea, and eukaryotes?

Accepted Answer

Viruses have the smallest genomes of these four types of organisms. Bacterial and archaean genomes are similar in size to each other. Eukaryotes have the largest genome sizes of these four groups. There is overlap among the groups, however, in that viral genome sizes overlap with genomes from archaea/bacteria, and eukaryote genome sizes overlap with genomes from archaea/bacteria.

Question 8

Match each of the following terms with its correct definition.
-transcriptome

Accepted Answer

A)  all proteins that can be produced by a cell
B)  all transcripts that are produced by a cell
C)  the study of all of the proteins produced from an organism's genome
D)  the study of genome sequences for several organisms
E)  the study of the whole genome of an organismF) the use of computer programs to extract biological information from sequence dataG) the study of all transcripts produced from an organism's genome

Question 9

Which of the following is the reason why the genes of living organisms tend to be similar to each other?

Accepted Answer

A)   All genes are old.
B)   All genes are new.
C)   They have evolved from ancestral genes in ancestral organisms.
D)   They have not evolved from ancestral genes in ancestral organisms.

Question 10

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below.
-cellular proteomics

Accepted Answer

A)  DNA
B)  mRNA/cDNA
C)  protein

Question 11

Match the following techniques with the descriptions listed below.
-used to decrease a gene's expression to see the effect

Accepted Answer

A)  whole-genome shotgun sequencing
B)  Illumina/Solexa sequencing
C)  Sanger sequencing
D)  DNA microarray analysis
E)  gene knockoutF) gene knockdown

Question 12

How can microarrays help us understand cellular functions?

Accepted Answer

A)   Microarrays let us study different cells under different conditions.
B)   Microarrays let us directly measure protein expression in individual cells.
C)   Microarrays, by hybridizing cDNAs to DNA sequences already present on a chip, let us identify which portions of a genome are being expressed in a cell at a particular time.
D)   Microarrays let us identify which DNA sequences are present in a particular cell type under certain conditions.

Question 13

In the microarray shown in your textbook, the cDNAs were labelled with red and green fluorescent tags. How then do you end up with spots on the microarray emitting yellow light?

Accepted Answer

A)   In light, red and green are two of the primary colours, and the combination of the two will produce yellow light.
B)   The yellow light comes from the laser, and a yellow spot indicates that neither cDNA hybridized to that spot on the microarray.
C)   The over expression of one cDNA relative to the other will skew the colour pattern of the spot on the microarray. This results in the yellow colour.
D)   The colour choice was an arbitrary decision by the artist and doesn't reflect how the process actually works.

Question 14

Which of the following is NOT an example of a current use of bioinformatics?

Accepted Answer

A)   locating individual genes in a genomic sequence
B)   aligning sequences in databases to determine similarities between organisms
C)   predicting the structure and function of gene products
D)   determining the final protein structure of novel proteins based on just the nucleotide sequence D

Question 15

Which of the following is NOT added to a single-stranded DNA in order to perform a successful sequencing reaction?

Accepted Answer

A)   a mixture of the four dideoxyribonucleotides, not labelled with a different fluorescent label
B)   a DNA primer
C)   a mixture of the four deoxyribonucleotides
D)   a DNA polymerase

Question 16

Which of the following is the name of the study of the complete set of transcripts in a cell?

Accepted Answer

A)   genome
B)   transcriptome
C)   proteome
D)   interactome

Question 17

What are the main differences among the studies of genomics, transcriptomics, and proteomics?

Accepted Answer

Genomics is the study of whole genomes a...

Question 18

Explain how proteomics is considered by some to be even more important than genome sequencing.

Accepted Answer

There are limits to what genome sequenci...

Question 19

Which of these techniques would a company that analyzes personal genomes most likely use?

Accepted Answer

A)   DNA cloning
B)   gene cloning
C)   PCR
D)   fingerprinting

Question 20

Match the following techniques with the descriptions listed below.
-used to replace a normal gene with a defective one to see the effect

Accepted Answer

A)  whole-genome shotgun sequencing
B)  Illumina/Solexa sequencing
C)  Sanger sequencing
D)  DNA microarray analysis
E)  gene knockoutF) gene knockdown E

Exam 15: Genomes

Which of the following is your "C-value"?

Correct Answer
verified

Match the following techniques with the descriptions listed below. -used to compare the gene expression patterns of identical cells under different conditions

Correct Answer
verified

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -genomics

Correct Answer
verified

Which of these statements best describes the human genome?

Correct Answer
verified

Which of the following is NOT a model organism whose genomes were sequenced as part of the original Human Genome Project?

Correct Answer
verified

Which of the following is NOT considered a source of evolving genes?

Correct Answer
verified

What are the relationships among the following types of organisms with respect to genome size: viruses, bacteria, archaea, and eukaryotes?

Match each of the following terms with its correct definition. -transcriptome

Correct Answer
verified

Which of the following is the reason why the genes of living organisms tend to be similar to each other?

Correct Answer
verified

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -cellular proteomics

Correct Answer
verified

Match the following techniques with the descriptions listed below. -used to decrease a gene's expression to see the effect

Correct Answer
verified

How can microarrays help us understand cellular functions?

Correct Answer
verified

In the microarray shown in your textbook, the cDNAs were labelled with red and green fluorescent tags. How then do you end up with spots on the microarray emitting yellow light?

Correct Answer
verified

Which of the following is NOT an example of a current use of bioinformatics?

Correct Answer
verified
D

Which of the following is NOT added to a single-stranded DNA in order to perform a successful sequencing reaction?

Correct Answer
verified

Which of the following is the name of the study of the complete set of transcripts in a cell?

Correct Answer
verified

What are the main differences among the studies of genomics, transcriptomics, and proteomics?

Correct Answer
verified
Genomics is the study of whole genomes a...
View Answer

Explain how proteomics is considered by some to be even more important than genome sequencing.

Correct Answer
verified
There are limits to what genome sequenci...
View Answer

Which of these techniques would a company that analyzes personal genomes most likely use?

Correct Answer
verified

Match the following techniques with the descriptions listed below. -used to replace a normal gene with a defective one to see the effect

Correct Answer
verified
E

Exam 15: Genomes

Which of the following is your "C-value"?

Correct AnswerverifiedShow Answer

Match the following techniques with the descriptions listed below. -used to compare the gene expression patterns of identical cells under different conditions

Correct AnswerverifiedShow Answer

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -genomics

Correct AnswerverifiedShow Answer

Which of these statements best describes the human genome?

Correct AnswerverifiedShow Answer

Which of the following is NOT a model organism whose genomes were sequenced as part of the original Human Genome Project?

Correct AnswerverifiedShow Answer

Which of the following is NOT considered a source of evolving genes?

Correct AnswerverifiedShow Answer

What are the relationships among the following types of organisms with respect to genome size: viruses, bacteria, archaea, and eukaryotes?

Match each of the following terms with its correct definition. -transcriptome

Correct AnswerverifiedShow Answer

Which of the following is the reason why the genes of living organisms tend to be similar to each other?

Correct AnswerverifiedShow Answer

For each of the following statements, choose the most appropriate macromolecule being studied or manipulated from the list below. -cellular proteomics

Correct AnswerverifiedShow Answer

Match the following techniques with the descriptions listed below. -used to decrease a gene's expression to see the effect

Correct AnswerverifiedShow Answer

How can microarrays help us understand cellular functions?

Correct AnswerverifiedShow Answer

In the microarray shown in your textbook, the cDNAs were labelled with red and green fluorescent tags. How then do you end up with spots on the microarray emitting yellow light?

Correct AnswerverifiedShow Answer

Which of the following is NOT an example of a current use of bioinformatics?

Correct AnswerverifiedD

Which of the following is NOT added to a single-stranded DNA in order to perform a successful sequencing reaction?

Correct AnswerverifiedShow Answer

Which of the following is the name of the study of the complete set of transcripts in a cell?

Correct AnswerverifiedShow Answer

What are the main differences among the studies of genomics, transcriptomics, and proteomics?

Correct AnswerverifiedGenomics is the study of whole genomes a...View AnswerShow Answer

Explain how proteomics is considered by some to be even more important than genome sequencing.

Correct AnswerverifiedThere are limits to what genome sequenci...View AnswerShow Answer

Which of these techniques would a company that analyzes personal genomes most likely use?

Correct AnswerverifiedShow Answer

Match the following techniques with the descriptions listed below. -used to replace a normal gene with a defective one to see the effect

Correct AnswerverifiedE

Correct Answer
verified

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D

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verified

Correct Answer
verified
Genomics is the study of whole genomes a...
View Answer

Correct Answer
verified
There are limits to what genome sequenci...
View Answer

Correct Answer
verified

Correct Answer
verified
E