Exam 16: Adaptive Immunity

A) growth factors
B) interferons
C) interleukins
D) tumor necrosis factors
E) chemokines

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A) the bone marrow
B) the spleen
C) the liver
D) both the bone marrow and the spleen
E) the thymus

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A) interaction between a T cell and an antigen-presenting cell to produce a specialized cell-to-cell contact area.
B) activation of a B cell to become a plasma cell.
C) interaction between lymphocytes and foreign antigens to produce memory cells.
D) binding of a monocyte or macrophage to antigen so that it can act as an antigen-presenting cell.
E) interaction of the many cytokines produced by different immunological cells.

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A) appendix.
B) lymph nodes of the groin.
C) lymph nodes of the neck (cervical) .
D) lymph nodes of the armpit (axilla) .
E) spleen.

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A) T lymphocytes that respond to autoantigens in the thymus undergo clonal deletion.
B) T lymphocytes require a specific set of cytokine signals to become activated.
C) Regulatory T cells suppress autoimmune responses.
D) Clonal deletion of T cells and regulatory T cell suppression prevent autoreactive T cell activation.
E) Clonal deletion of T cells, lack of necessary cytokine signals, and regulatory T cell suppression prevent activation of autoreactive T cells.

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A) the appendix
B) the spleen
C) Peyer's patches
D) lymphoid tissue in the respiratory tract
E) lymphoid tissue in the small intestine

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A) They cause basophils and eosinophils to degranulate.
B) They are the most common type of antibody in the blood during the initial stages of an immune response.
C) They are the antibody class found in body secretions.
D) They interact with phagocytes and NK cells.
E) They can cross the placenta to provide passive immunity.

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A) T lymphocytes produce antibody molecules.
B) T lymphocytes directly attack cells and produce the cell-mediated immune response.
C) T lymphocytes are called such because they mature in the thymus.
D) T lymphocytes have TCRs that recognize antigen only if it is bound to MHC.
E) There are three types of T lymphocytes.

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A) T cells
B) B cells
C) NK cells
D) dendritic cells
E) macrophages

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A) activation of the dendritic cell to become a plasma cell
B) display of epitope-MHC I complexes on the surface of the cell
C) suppression of the immune response to the microbe
D) display of microbial fragments with CD8 glycoproteins
E) display of microbial epitope-MHC II complexes on the cell surface

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A) artificial passive
B) natural passive
C) natural active
D) artificial active
E) both active and passive

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A) alpha interferon
B) chemokines
C) tumor necrosis factor (TNF)
D) IL-4 (interleukin-4)
E) IL-12

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A) red blood cells do not produce MHC and, therefore, do not display the fact that they have been infected by presenting antigen.
B) the parasite damages leukocytes along with RBCs.
C) RBCs normally produce cytokines necessary for adaptive immune response, which this infection prevents.
D) complement cannot effectively destroy RBCs.
E) RBCs never enter lymphoid tissue.

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