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Individuals with three or more copies of each of their chromosomes are called ____. ​


A) polyploids ​
B) haploids
C) aneuploids
D) euploids
E) diploids

Correct Answer

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The presence of genes that encode many types of hemoglobin in mammals, but not in other vertebrates that evolved earlier, is evidence of ____ of genetic material. ​


A) an inversion ​
B) the duplication
C) reciprocal translocation
D) the deletion
E) both duplication and deletion

Correct Answer

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B

Choose the mode of inheritance that has been determined for each of the following genetic conditions in humans. Some choices may be used more than once.

Premises
achondroplasia
Responses
aneuploidy
autosomal dominant
autosomal recessive
X-linked recessive
X-linked dominant

Correct Answer

aneuploidy
autosomal dominant
autosomal recessive
X-linked recessive
X-linked dominant

You are a genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have hemophilia. The woman has an X-linked recessive form of hemophilia, but the man does not. How should you advise them?


A) Half of their children will have hemophilia.. ​
B) All of their sons and half of their daughters will have hemophilia.
C) None of their children will have hemophilia, but all of their daughters will be carriers for hemophilia.
D) Each of their sons will have a 50% chance of having hemophilia, and each of their daughters will have a 50% chance of being carriers.
E) All of their sons will have hemophilia, and all of their daughters will be carriers.

Correct Answer

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An autosome is a ____. ​


A) chromosome other than a sex chromosome
B) structure used to transport genetic material to the cytoplasm
C) chromosome containing a group of genes involved in autoimmune disorders
D) region of the DNA that is self-replicating
E) cellular body involved in autoimmune disorders

Correct Answer

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During normal human embryonic development, if ____, then the SRY gene switches development toward ____. ​


A) a Y chromosome is present; maleness ​
B) an X chromosome is present; femaleness
C) two X chromosomes are present; femaleness
D) the X chromosome is absent; maleness
E) a Y chromosome is present; femaleness

Correct Answer

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Genetic studies of an animal show that eye color is controlled by an autosomal gene with the dominant allele ( R ) for red eye color and the recessive allele ( r ) for yellow eye color. A second autosomal gene has the dominant allele ( T ) for paws with thumbs and the recessive allele ( t ) for paws without thumbs. The genetic cross RRTT x rrtt creates offspring with genotype RrTt . One of those dihybrids is mated in a testcross ( RrTt x rrtt ) . Based on the principle of independent assortment, the testcross should produce offspring with the phenotype ratio ____.


A) 3 red-eyed with thumbs : 1 yellow-eyed without thumbs ​
B) 1 red-eyed with thumbs : 1 yellow-eyed with thumbs: 1 red-eyed without thumbs: 1 yellow-eyed without thumbs
C) 1 red-eyed with thumbs : 1 yellow-eyed without thumbs
D) 9 red-eyed with thumbs : 3 yellow-eyed with thumbs: 3 red-eyed without thumbs: 1 yellow-eyed without thumbs
E) 3 yellow-eyed with thumbs : 1 red-eyed without thumbs

Correct Answer

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About 4% of individuals of Northern European descent are carriers for ____, an autosomal recessive genetic disorder in which a defective membrane transport protein leads to deficient chloride levels in extracellular fluids. ​


A) Duchenne muscular dystrophy ​
B) phenylketonuria
C) achondroplasia
D) sickle-cell anemia
E) cystic fibrosis

Correct Answer

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  Figure 13.4 The change in the chromosome depicted between the top and the bottom in the accompanying figure represents a(n) ____. A) inversion B) duplication C) reciprocal translocation D) deletion E) Philadelphia chromosome Figure 13.4 The change in the chromosome depicted between the top and the bottom in the accompanying figure represents a(n) ____.


A) inversion
B) duplication
C) reciprocal translocation
D) deletion
E) Philadelphia chromosome

Correct Answer

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Choose the mode of inheritance that has been determined for each of the following genetic conditions in humans. Some choices may be used more than once.

Premises
Duchenne muscular dystrophy
Responses
autosomal recessive
X-linked recessive
X-linked dominant
aneuploidy
autosomal dominant

Correct Answer

autosomal recessive
X-linked recessive
X-linked dominant
aneuploidy
autosomal dominant

Choose the mode of inheritance that has been determined for each of the following genetic conditions in humans. Some choices may be used more than once.

Premises
red-green colorblindness
Responses
X-linked dominant
autosomal dominant
X-linked recessive
autosomal recessive
aneuploidy

Correct Answer

X-linked dominant
autosomal dominant
X-linked recessive
autosomal recessive
aneuploidy

Most hospitals in the United States routinely test all newborns for ____, an autosomal recessive disorder in which a metabolic abnormality causes a buildup of compounds that damage brain tissue and can lead to mental retardation unless a restricted diet is followed.


A) Duchenne muscular dystrophy ​
B) phenylketonuria
C) achondroplasia
D) sickle-cell anemia
E) cystic fibrosis

Correct Answer

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Chemical compounds released during tobacco use can cause ____.


A) sickle-cell anemia ​
B) color blindness
C) cancer
D) cystic fibrosis
E) hemophilia

Correct Answer

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If a hypothetical human female of genotype XX had no Barr body in any of her cells, ---____. ​


A) she would be phenotypically male
B) she would be considered triploid
C) the genes on both X chromosomes would be expressed ​
D) she would have Turner syndrome
E) she would have a Y chromosome

Correct Answer

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In humans, an extra copy of chromosome 21 typically leads to moderate to severe mental retardation and sterility, as well as to a greater likelihood of heart defects and other problems. This disorder is known as ____.


A) Turner syndrome ​
B) Down syndrome
C) cri-du-chat
D) Triple-X syndrome
E) Klinefelter syndrome

Correct Answer

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You are a genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have hemophilia. Neither of them has hemophilia, but the woman's biological father did have an X-linked recessive form of hemophilia. How should you advise them? ​


A) Half of their children will have hemophilia.
B) All of their sons and half of their daughters will have hemophilia.
C) None of their children will have hemophilia, but all of their daughters will be carriers for hemophilia.
D) Each of their sons will have a 50% chance of having hemophilia, and each of their daughters will have a 50% chance of being carriers.
E) All of their sons will have hemophilia, and all of their daughters will be carriers.

Correct Answer

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You are a genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have cystic fibrosis. Genetic tests reveal that the woman is a carrier for cystic fibrosis but the man is not. How should you advise them? ​


A) Half of their children will have cystic fibrosis, and the other half will be carriers. ​
B) All of their children will have cystic fibrosis.
C) There are no concerns, because none of their offspring have a chance of inheriting the cystic fibrosis allele.
D) While none of their children will have cystic fibrosis, each child will have a 50% chance of being a carrier.
E) All of their children will have a 25% chance of having cystic fibrosis.

Correct Answer

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Suppose that you have discovered a new mutant in Drosophila melanogaster . The trait is known to be sex linked. Which crosses should you perform to determine if the mutant trait is recessive or dominant?

Correct Answer

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You should do the following crosses:
Cr...

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About 10-15% of African Americans in the US are carriers for ____, an autosomal recessive genetic disorder in which a defective version of the hemoglobin protein is produced. ​


A) Duchenne muscular dystrophy ​
B) phenylketonuria
C) achondroplasia
D) sickle-cell anemia
E) cystic fibrosis

Correct Answer

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D

Choose the mode of inheritance that has been determined for each of the following genetic conditions in humans. Some choices may be used more than once.

Premises
hereditary enamel hydroplasia
Responses
X-linked dominant
autosomal dominant
X-linked recessive
aneuploidy
autosomal recessive

Correct Answer

hereditary enamel hydroplasia
X-linked dominant

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