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Recombination frequency for two genes is a function of the ____.


A) distance between the two genes on a single chromosome
B) overall size of the chromosome on which the genes are located
C) distance between the two chromosomes on which the two genes are located
D) relative sizes of the two chromosomes on which the two genes are located
E) sex of the parent that supplies each gene

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Genetic studies of an animal show that eye color is controlled by an autosomal gene with the dominant allele ( R ) for red eye color and the recessive allele ( r ) for yellow eye color. A second autosomal gene has the dominant allele ( T ) for paws with thumbs and the recessive allele ( t ) for paws without thumbs. The genetic cross RRTT x rrtt creates offspring with genotype RrTt . One of those dihybrids is mated in a testcross ( RrTt x rrtt ) . If the two genes are completely linked (no recombination occurs between them) , then the testcross should produce offspring with the phenotype ratio ____.


A) three red-eyed with thumbs: one yellow-eyed without thumbs
B) one red-eyed with thumbs: one yellow-eyed with thumbs: one red-eyed without thumbs: one yellow-eyed without thumbs
C) one red-eyed with thumbs: one yellow-eyed without thumbs
D) nine red-eyed with thumbs: three yellow-eyed with thumbs: three red-eyed without thumbs: one yellow-eyed without thumbs
E) one yellow-eyed with thumbs: one red-eyed without thumbs

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You are a genetic counselor, and a couple comes to you with concerns that if they have a child together, he or she could have hemophilia. The woman has an X-linked recessive form of hemophilia, but the man does not. How should you advise them?


A) Half of their children will have hemophilia.
B) All of their sons and half of their daughters will have hemophilia.
C) None of their children will have hemophilia, but all of their daughters will be carriers for hemophilia.
D) Each of their sons will have a 50% chance of having hemophilia, and each of their daughters will have a 50% chance of being carriers.
E) All of their sons will have hemophilia, and all of their daughters will be carriers.

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  2014 Examine the pedigree in the accompanying figure. Individuals affected by the genetic condition in question are indicated by filled squares or circles. Which inheritance pattern is most likely correct for this condition in this family? A)  autosomal dominant B)  X-linked recessive C)  X-linked dominant D)  cytoplasmic inheritance E)  autosomal recessive 2014 Examine the pedigree in the accompanying figure. Individuals affected by the genetic condition in question are indicated by filled squares or circles. Which inheritance pattern is most likely correct for this condition in this family?


A) autosomal dominant
B) X-linked recessive
C) X-linked dominant
D) cytoplasmic inheritance
E) autosomal recessive

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Which process exchanges alleles between homologous chromosomes?


A) mitosis
B) genetic recombination
C) asexual reproduction
D) independent assortment
E) anaphase

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The product of the ABL gene is a ______.


A) hormone
B) tyrosine phosphatase
C) tyrosine kinase
D) hormone receptor
E) protein kinase

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About 10-15% of African Americans in the US are carriers for ____, an autosomal recessive genetic disorder in which a defective version of the hemoglobin protein is produced.


A) Duchenne muscular dystrophy
B) phenylketonuria
C) achondroplasia
D) sickle-cell anemia
E) cystic fibrosis

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Which condition would most likely lead to an apparently normal human female?


A) Turner syndrome
B) Down syndrome
C) cri-du-chat
D) Triple-X syndrome
E) Klinefelter syndrome

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  2014 Examine the pedigree in the accompanying figure. Individuals affected by the genetic condition in question are indicated by filled squares or circles. Which inheritance pattern is most likely correct for this condition in this family? A)  autosomal dominant B)  X-linked recessive C)  X-linked dominant D)  cytoplasmic inheritance E)  autosomal recessive 2014 Examine the pedigree in the accompanying figure. Individuals affected by the genetic condition in question are indicated by filled squares or circles. Which inheritance pattern is most likely correct for this condition in this family?


A) autosomal dominant
B) X-linked recessive
C) X-linked dominant
D) cytoplasmic inheritance
E) autosomal recessive

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This autosomal dominant genetic trait is associated with a gene on human chromosome 4 and causes a type of dwarfing due to defective cartilage formation.


A) Duchenne muscular dystrophy
B) phenylketonuria
C) achondroplasia
D) sickle-cell anemia
E) cystic fibrosis

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As an undergraduate research assistant, you are given a genetic mapping project. You are told that genes a and b are 7.4 map units from each other and that genes b and c are 5.7 map units from each other. You perform a testcross to determine the map distance between a and c . Which of the following results would indicate that c lies between a and b ?


A) 11.1 map units
B) 15.0 map units
C) 2.0 map units
D) 14.8 map units
E) 13.1 map units

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A woman with normal blood clotting mates with a man who also has normal blood clotting. Their first child is a boy who has hemophilia. Tests show that the child's hemophilia is X-linked and that he has normal genetic inheritance. You can predict that if the couple has more children together, then it is likely that ____.


A) all of the children will have hemophilia
B) half of the boys and none of the girls will have hemophilia
C) none of the rest of children should have hemophilia
D) all of the boys and half of the girls will have hemophilia
E) half of the boys and half of the girls will have hemophilia

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Suppose that you have discovered a new mutant in Drosophila melanogaster . The trait is known to be sex linked. Which crosses should you perform to determine if the mutant trait is recessive or dominant?

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You should do the following crosses:
Cr...

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Carriers of the sickle-cell allele have a genetic advantage because they have ____.


A) lower blood pressure
B) the ability to carry more oxygen in their blood
C) increased resistance to malaria
D) hyperactive immune systems
E) extra red blood cells

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The X chromosome ____.


A) carries the SRY gene
B) is present in two copies in males
C) pairs with an autosome during meiosis
D) carries many genes that are not involved in sex determination
E) is not present in males

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Which statement correctly describes the inheritance of sex chromosomes?


A) A woman will pass on a specific X chromosome to all of her daughters.
B) A woman will pass on an X chromosome to half of her children.
C) A woman will pass on an X chromosome to all of her children.
D) A woman's genetic contribution determines the sex of her children.
E) A man will pass on an X chromosome to all of his children.

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The presence of genes that encode many types of hemoglobin in mammals, but not in other vertebrates that evolved earlier, is evidence of ____ of genetic material.


A) an inversion
B) the duplication
C) reciprocal translocation
D) the deletion
E) both duplication and deletion

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Your cousin learns that she is a carrier for phenylketonuria (PKU). Her husband's biological mother has PKU. She asks you to explain what this could mean if she and her husband have children and asks what, if anything, could be done to best protect any child that may have. What would you tell her?

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First, I would tell her that PKU is easi...

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In humans, sex determination generally depends upon the ____.


A) presence of the X chromosome
B) number of X chromosomes present
C) environment in the womb
D) presence of the Y chromosome
E) number of autosomes

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In humans, an extra copy of chromosome 21 typically leads to moderate to severe mental retardation and sterility, as well as to a greater likelihood of heart defects and other problems. This disorder is known as ____.


A) Turner syndrome
B) Down syndrome
C) cri-du-chat
D) Triple-X syndrome
E) Klinefelter syndrome

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