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________ are proteins that promote depolymerization of extant microtubules at the ends.

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Catastroph...

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Which of the following is not a cellular activity associated with microtubules?


A) maintenance of axons
B) cell shape
C) orientation of cellulose microfibrils
D) cilial structure
E) mititotic spindle

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A unique feature of ________ is that they are tissue specific.

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intermedia...

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The ________ model was proposed by Mitchison and Kirschner to explain how polymerization and depolymerization of microtubules occur simultaneously.

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Choose the item that best matches the other items. -myosin subfragment 1 (S1)


A) breaking and capping actin
B) increase cellular surface area
C) assembly and disassembly
D) terminal web
E) control microtubule organization
F) plectin
G) central shaft
H) nucleating actin branches
I) bind to profilin and CapZ
J) oligomer formation
K) nucleating tubulin branches
L) hemidesmosome
M) decorate the actin microfilament
N) dynein
O) prevents loss of subunits
P) desmosome
Q) nuclear lamina
R) account for 10-15% of microtubules
S) inhibits microtubule assembly
T) two identical polypeptides joined end-to-end
U) found in cilia and flagella

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You have discovered a new cytoskeletal element and need to identify and characterize it for further work.How would you go about examining this protein to ultimately classify it as a cytoskeletal element?

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First,identify the subunit and determine...

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Cytoskeletal elements are found in the


A) Eubacteria.
B) Archaea.
C) Eukarya.
D) choices B and C only
E) all of the above

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Which of the following is not a function of the cytoskeleton?


A) cell movement
B) cell division
C) moving of organelles
D) positioning of enzymes
E) passive transport

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________ causes microtubules to form tight bundles in nerve cells.


A) Dynein
B) Actin
C) Tau
D) Kinesis
E) Tubulin

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All of the following are moved by molecular motors except


A) secretory vesicles.
B) cytoskeletal filaments.
C) the Golgi complex.
D) glucose.
E) chloroplasts.

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Choose the item that best matches the other items. -microtubule-associated proteins (MAPs)


A) breaking and capping actin
B) increase cellular surface area
C) assembly and disassembly
D) terminal web
E) control microtubule organization
F) plectin
G) central shaft
H) nucleating actin branches
I) bind to profilin and CapZ
J) oligomer formation
K) nucleating tubulin branches
L) hemidesmosome
M) decorate the actin microfilament
N) dynein
O) prevents loss of subunits
P) desmosome
Q) nuclear lamina
R) account for 10-15% of microtubules
S) inhibits microtubule assembly
T) two identical polypeptides joined end-to-end
U) found in cilia and flagella

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Match the group of proteins with an example from the other group.

Premises
capping protein
nonmotor MAP
motor MAP
linker proteins
Responses
CapB
Tau
spectrin
alpha
kinesin
CapZ

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CapB
Tau
spectrin
alpha
kinesin
CapZ

Choose the item that best matches the other items. -polyphosphoinositides


A) breaking and capping actin
B) increase cellular surface area
C) assembly and disassembly
D) terminal web
E) control microtubule organization
F) plectin
G) central shaft
H) nucleating actin branches
I) bind to profilin and CapZ
J) oligomer formation
K) nucleating tubulin branches
L) hemidesmosome
M) decorate the actin microfilament
N) dynein
O) prevents loss of subunits
P) desmosome
Q) nuclear lamina
R) account for 10-15% of microtubules
S) inhibits microtubule assembly
T) two identical polypeptides joined end-to-end
U) found in cilia and flagella

Correct Answer

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One of the following drugs blocks cell division because it stabilizes the microtubules.What is this drug,and for what is it used?


A) vincristine; bacterial infections
B) vinblastine; antimitotic therapy
C) taxol; breast cancer
D) nocodazole; allergies
E) benzimidazole; colchicine

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