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Neutrophils,eosinophils,and basophils are called ________ because they have prominent cytoplasmic inclusions that,in a stained blood smear,appear with identifying,characteristic colors.


A) leukocytes
B) granulocytes
C) agranulocytes
D) monocytes
E) None of the choices are correct.

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Each of the following are benefits of fever except it ________.


A) reduces the ability of temperature-sensitive organisms to multiply
B) increases the availability of iron
C) increases phagocytosis
D) increases metabolism
E) stimulates hematopoiesis

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Components of the first line of defense include all the following except ________.


A) the tough cell sheet of the upper epidermis of the skin
B) nasal hairs
C) flushing action of tears and blinking
D) flushing action of urine
E) phagocytic white blood cells

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The leakage of excess fluid into tissues is called ________.


A) chemotaxis
B) edema
C) diapedesis
D) vasoactivity
E) pus

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The membrane attack stage of the complement cascade involves ________.


A) initiation of the cascade
B) production of inflammatory cytokines
C) a ring-shaped protein that digests holes in bacterial cell membranes and virus envelopes
D) cleaving of C3 to yield C3a and C3b
E) C1q binding to surface receptors on a membrane

Correct Answer

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Each of the following are granulocytes except ________.


A) neutrophils
B) eosinophils
C) lymphocytes
D) basophils
E) All of the choices are granulocytes.

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A 35-year-old male presents to the ER with a laceration on his left hand. The patient reports an hour ago he was working on renovations in his 1945 home, when an old board fell and injured his hand. The laceration is approximately 3 inches long and moderately deep. It appears that the cut was bleeding heavily, but he has stopped the bleeding by holding pressure on the site with an old t-shirt. -Which line(s) of defense has been breached for this injury? 


A) First line of defense
B) Second line of defense
C) First and second lines of defense
D) First,second and third lines of defense

Correct Answer

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Which of the following is a chemical used by phagocytes to destroy ingested foreign substances?


A) Hydrogen peroxide
B) Nitric oxide
C) Lactic acid
D) Superoxide anion
E) All of these are used.

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Which white blood cells comprise 20% to 30% of the circulating WBCs and are the cells that function in the body's third line of defense?


A) Basophils
B) Eosinophils
C) Neutrophils
D) Monocytes
E) Lymphocytes

Correct Answer

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The least numerous of all white blood cells that release histamine during inflammation and allergic reactions are ________.


A) basophils
B) eosinophils
C) neutrophils
D) monocytes
E) lymphocytes

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Cytokines are chemicals and proteins that are critical components of the immune system.  Which of the following statements is incorrect regarding the function of cytokines?


A) All cytokines are synthesized to stimulate the inflammatory response; their purpose is to mediate vascular reactions and diapedesis.
B) Cytokines are secreted by a wide variety of cell types,including immune cells,epithelial and endothelial cells.
C) Cytokines play a role in both inflammatory stimulation,as well as being anti-inflammatory mediators.
D) Cytokines mediate communication between cells; they are crucial for stimulation,suppression and control of all aspects of the immune response.

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What is the first step in the major events of the inflammation process?


A) Formation of pus and edema
B) Scar formation and/or resolution
C) Vascular reactions
D) Injury and mast cells releasing chemical mediators
E) Activation of the complement system

Correct Answer

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A 35-year-old male presents to the ER with a laceration on his left hand. The patient reports an hour ago he was working on renovations in his 1945 home, when an old board fell and injured his hand. The laceration is approximately 3 inches long and moderately deep. It appears that the cut was bleeding heavily, but he has stopped the bleeding by holding pressure on the site with an old t-shirt. -The patient states,"There has to be a way for me to reduce this swelling.There is no way this can be good for me because it is so uncomfortable." Which of the following statements by the nurse is not an appropriate response?


A) Swelling helps trap foreign microbes to prevent them from getting into your main circulation.
B) Inflammation is a sign that your immune system is fighting the effects of your skin barrier being broken.
C) The influx of fluid into the area is helping to dilute toxins.
D) Swelling is a result of your bones responding to the influx of calcium-fighting toxins.

Correct Answer

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Certain complement components stimulate inflammation and phagocytosis.

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Which statement below characterizes the action of interferon?


A) Interferon,produced by a host cell in response to viral attack,is secreted and enters neighboring cells,stimulating the production of antiviral proteins in anticipation of an invasion.
B) Interferon stimulates the hypothalamus to raise the body temperature,increasing metabolism and preventing the growth of temperature-sensitive pathogens.
C) Interferon comprises a team of blood proteins that are activated in a cascade,ultimately leading to pathogen cytolysis,inflammation and enhanced phagocytosis.
D) Interferon binds to cell surfaces and induces changes in genetic expression,eliminating not only pathogens,but cancer cells also.

Correct Answer

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Hematopoiesis is the ________.


A) loss of blood due to hemorrhaging
B) production of only red blood cells
C) production of white blood cells,red blood cells,and platelets
D) plugging of broken vessels to stop bleeding
E) migration of white blood cells from the blood out to the tissues

Correct Answer

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What structures are found along lymphatic vessels and are heavily clustered in the armpit,groin,and neck?


A) Lymph nodes
B) Thymus
C) Spleen
D) GALT
E) Tonsils

Correct Answer

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All the following are events of early inflammation except ________.


A) macrophages appear first and begin phagocytosis
B) chemical mediators and cytokines are released
C) brief vasoconstriction is followed by vasodilation
D) exudate and pus can accumulate
E) capillaries become more permeable resulting in edema

Correct Answer

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Which of the following is in the correct order from greatest to least phagocytic activity?


A) Neutrophils,eosinophils,macrophages
B) Neutrophils,macrophages,eosinophils
C) Eosinophils,macrophages,neutrophils
D) Macrophages,neutrophils,eosinophils
E) Macrophages,eosinophils,neutrophils

Correct Answer

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Which of the following is not a chief function of inflammation?


A) Start tissue repair
B) Destroy microbes
C) Mobilize and attract immune components to injury site
D) Block further invasion
E) Cause a fever

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