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The primary structure of a protein is directly associated with ______.


A) regular repeating shapes, such as beta-sheets
B) the three-dimensional shape of the protein
C) the linear sequence of the amino acids
D) the interaction of two or more peptide chains

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C

What typically stops the process of translation?


A) Rho proteins
B) Aminoacyl tRNA synthase
C) rRNA
D) Stop codons
E) Introns

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A polyribosome would be found in which of the following types of cells?


A) Prokaryotic
B) Eukaryotic
C) Both

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A protein called actin consists of 376 amino acids. The mRNA for actin must be longer than


A) 125 nucleotides.
B) 376 nucleotides.
C) 1128 nucleotides.
D) 3384 nucleotides.

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C

Where are the ribosomal subunits assembled in eukaryotes?


A) Nucleus
B) Nucleoid
C) Nucleolus
D) Nuclear envelope

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RF1 and RF2 are active during _______.


A) initiation
B) elongation
C) termination
D) peptidyl transfer

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A tRNA that has an amino acid attached is called _____.


A) an rRNA
B) a degenerate tRNA
C) a coding tRNA
D) a charged tRNA
E) None of the answers are correct

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Consider the following mRNA from a eukaryotic species. Which AUG codon is translation most likely to begin from? 5'-CCUAUGAGCCACCAUGGAUGCCAAAUGCA-3'


A) 1st
B) 2nd
C) 3rd
D) 4th

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Select the codon that is not synonymous with CUU.


A) CUC
B) UUG
C) CUA
D) AUU
E) UUA

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α\alpha -helices and β\beta -sheets are examples of what level of protein structure?


A) Primary structure
B) Secondary structure
C) Tertiary structure
D) Quanternary structure

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61 different tRNAs are required for translation both in vivo and in vitro.

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How many amino acids would be included in the polypeptide encoded by the following mRNA: 5'GCCACCAUGGGCCAAUUACGAAGGUUUUGCUGACCAGGUCAA3'


A) 7
B) 8
C) 10
D) 13

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What is the minimal number of tRNAs that can be used to recognize all of the codons for threonine?


A) 1
B) 2
C) 3
D) 4

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B

An anticodon is located on ______.


A) DNA
B) mRNA
C) rRNA
D) tRNA
E) snRNA

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The genetic code is universal in nuclear DNA from bacteria to mammals.

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You perform a cell free translation experiment like Nirenberg and Matthaei. You start with 60% C and 40% A. What relative amount of radiolabeled proline do you expect in the translated polypeptides?


A) 36%
B) 22%
C) 14%
D) 28%

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The C-terminus of a polypeptide always contains


A) a stop codon.
B) a carboxyl group.
C) an amino group.
D) carbon dioxide.
E) None of the answers are correct.

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In the digestive system of animals, proteins called amylases and proteases break down large molecules (for example, starches or proteins) into smaller ones so that they can be absorbed by the intestine. What category of protein function do these proteins fall into?


A) Cell shape or organization
B) Transport
C) Movement
D) Cell signaling
E)
Cell surface recognition
F)
Enzymes

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Select the amino acid that has been activated by aminoacyl-tRNA synthetase.


A) Amino acid · ATP · aminoacyl-tRNA synthetase
B) Amino acid · aminoacyl-tRNA synthetase
C) Amino acid + AMP + PPi
D) Amino acid · AMP

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What is true according to the adaptor hypothesis?


A) The anticodon and amino acid have no relationship.
B) A given tRNA can carry any of the twenty amino acids.
C) The position of an amino acid within a polypeptide is determined by the binding of mRNA with a tRNA carrying a specific amino acid.
D) An amino acid recognizes the codon in mRNA.

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