Question 1

The antibody-secreting progeny cells of a B-cell clone are called

Accepted Answer

A)   plasma cells.
B)   antibodies.
C)   bursa cells.
D)   activated macrophages.
E)   sensitized T cells.

Question 2

The adaptive immune system is complex,but it can be summarized in four consecutive stages: i)lymphocyte encounter with an immunogen,ii)development of lymphocyte specificity against that immunogen,iii)2nd encounter with the immunogen,and iv)development of memory cells.

Accepted Answer

A) True 
 B)False

Question 3

An example of natural active immunity would be

Accepted Answer

A)   chickenpox infection, followed by lifelong immunity.
B)   giving a person immune serum globulins to chickenpox virus after exposure to the disease.
C)   a fetus acquiring maternal IgG to the chickenpox virus across the placenta.
D)   chickenpox vaccine triggering extended immunity to chickenpox. A

Question 4

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Accepted Answer

A)   Opsonization
B)   Agglutination
C)   Anamnestic response
D)   Neutralization
E)   Complement fixation

Question 5

All of the following are characteristics of IgM except

Accepted Answer

A)   it can serve as a B-cell receptor.
B)   it is a dimer.
C)   it is the first class synthesized by a plasma cell.
D)   it has 10 antigen binding sites.
E)   it contains a central J chain.

Question 6

After secreting antibodies during an immune response,plasma cells then differentiate into memory cells.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following is not a property of B cells?

Accepted Answer

A)   They produce plasma cells and memory cells.
B)   They have receptors called immunoglobulins.
C)   They mature in the bone marrow.
D)   They require antigen presented with MHC proteins.
E)   There are low numbers circulating in the blood.

Question 8

Antigens that elicit allergic reactions are called ______.

Accepted Answer

A)   allergens
B)   autoantigens
C)   superantigens
D)   heterophilic antigens A

Question 9

The adaptive immune response differs from the innate response in that

Accepted Answer

A)  	the adaptive immune response targets specific immunogens and remembers them, mounting an even stronger response on subsequent encounters, whereas the innate response is nonspecific and has no memory.
B)  	B and T lymphocytes can each target multiple proteins, whereas the innate response targets only a single type of antigen.
C)  	the adaptive immune response involves physical barriers and nonspecific processes, whereas the innate immune response relies on the actions of B and T lymphocytes.
D)  	the innate immune response targets a specific immunogen and remembers it to mount an even stronger response on subsequent encounters with that immunogen, whereas the adaptive response is nonspecific and has no memory. A

Question 10

Superantigens are

Accepted Answer

A)   body tissues that the immune system mistakes as foreign.
B)   cell markers found in some member of a species but not in other members.
C)   bacterial toxins that activate T cells at a 100 times greater rate than other antigens.
D)   antigens that evoke allergic reactions.

Question 11

An example of artificial active immunity would be

Accepted Answer

A)   chickenpox vaccine triggering extended immunity to chickenpox.
B)   a fetus acquiring maternal IgG to the chickenpox virus across the placenta.
C)   giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D)   chickenpox infection, followed by lifelong immunity.

Question 12

Human B lymphocytes mature in an intestinal region called the bursa.

Accepted Answer

A) True 
 B)False

Question 13

Acellular vaccines and subunit vaccines

Accepted Answer

A)   contain modified bacterial exotoxin molecules.
B)   contain select antigenic components of a pathogen rather than whole cells or viruses.
C)   utilize DNA strands that will produce the antigen.
D)   confer passive immunity.
E)   are always genetically engineered.

Question 14

As an adult who never developed chickenpox infection as a child,you elect to receive the protective vaccine against this pathogen at the age of 35.This vaccine will stimulate

Accepted Answer

A)   latency.
B)   an anamnestic response.
C)   a primary immune response.
D)   a secondary immune response.

Question 15

Class II MHC genes code for

Accepted Answer

A)   certain secreted complement components.
B)   self receptors recognized by T lymphocytes.
C)   all HLA antigens.
D)   receptors located primarily on macrophages and B cells.
E)   All of the choices are correct.

Question 16

MHC molecules are found on all of the following cells except ______.

Accepted Answer

A)   red blood cells
B)   epithelial cells
C)   eosinophils
D)   islet of Langerhans cells
E)   leukocytes

Question 17

The embryonic yolk sac,the liver,and the bone marrow are sites where

Accepted Answer

A)   T lymphocytes complete maturation.
B)   immune responses to antigen occur.
C)   stem cells give rise to immature lymphocytes.
D)   antigen is filtered from the blood.
E)   antigen is filtered from tissue fluid.

Question 18

Edward Jenner's work involved

Accepted Answer

A)   development of passive immunotherapy.
B)   immunization using a related, less pathogenic organism to give protection against a more pathogenic one.
C)   development of an immunization to protect people against cowpox.
D)   inoculation of dried pus from smallpox pustules into a person to stimulate immunity.

Question 19

Antigen presenting cells

Accepted Answer

A)   include dendritic cells.
B)   include macrophages.
C)   engulf and modify antigen to be more immunogenic.
D)   hold and present processed antigen on their cell membrane surface.
E)   All of the choices are correct.

Question 20

Vaccinia virus is often used in the technique to make

Accepted Answer

A)   a booster.
B)   gamma globulin.
C)   an adjuvant.
D)   a "Trojan horse" recombinant vaccine.
E)   antibodies to toxin.

Exam 15: Host Defenses II: Specific Immunity and Immunization

The antibody-secreting progeny cells of a B-cell clone are called

Correct AnswerverifiedShow Answer

The adaptive immune system is complex,but it can be summarized in four consecutive stages: i)lymphocyte encounter with an immunogen,ii)development of lymphocyte specificity against that immunogen,iii)2nd encounter with the immunogen,and iv)development of memory cells.

Correct AnswerverifiedShow Answer

An example of natural active immunity would be

Correct AnswerverifiedA

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Correct AnswerverifiedShow Answer

All of the following are characteristics of IgM except

Correct AnswerverifiedShow Answer

After secreting antibodies during an immune response,plasma cells then differentiate into memory cells.

Correct AnswerverifiedShow Answer

Which of the following is not a property of B cells?

Correct AnswerverifiedShow Answer

Antigens that elicit allergic reactions are called ______.

Correct AnswerverifiedA

The adaptive immune response differs from the innate response in that

Correct AnswerverifiedA

Superantigens are

Correct AnswerverifiedShow Answer

An example of artificial active immunity would be

Correct AnswerverifiedShow Answer

Human B lymphocytes mature in an intestinal region called the bursa.

Correct AnswerverifiedShow Answer

Acellular vaccines and subunit vaccines

Correct AnswerverifiedShow Answer

As an adult who never developed chickenpox infection as a child,you elect to receive the protective vaccine against this pathogen at the age of 35.This vaccine will stimulate

Correct AnswerverifiedShow Answer

Class II MHC genes code for

Correct AnswerverifiedShow Answer

MHC molecules are found on all of the following cells except ______.

Correct AnswerverifiedShow Answer

The embryonic yolk sac,the liver,and the bone marrow are sites where

Correct AnswerverifiedShow Answer

Edward Jenner's work involved

Correct AnswerverifiedShow Answer

Antigen presenting cells

Correct AnswerverifiedShow Answer

Vaccinia virus is often used in the technique to make

Correct AnswerverifiedShow Answer

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