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The analytical method that provides better analytical sensitivity in hormone detection than other methods such as immunoassay or receptor-based assays is:


A) tandem mass spectrometry.
B) bioassay.
C) immunometric assay.
D) spectrophotometry.

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An example of a protein hormone synthesized in the hypothalamus,with the principal action to control the release of thyroid-stimulating hormone,is:


A) prolactin.
B) thyroid stimulating hormone.
C) ACTH.
D) thyrotropin releasing hormone.

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D

Considering the classification of hormones by structure,an example of a steroid hormone would be:


A) testosterone.
B) parathyroid hormone (PTH) .
C) cortisol.
D) all of the above.

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An example of a polypeptide hormone that is part of the complex integrative function of many hormones involved in development of the human organism is:


A) growth hormone.
B) estrogen.
C) cortisol.
D) thyroxine.

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Which one of the following statements concerning protein hormones is correct?


A) A protein hormone binds to a receptor within the cell or on the nucleus of the cell,thereby directly affecting protein synthesis.
B) A protein hormone,once bound to its receptor,activates adenylyl cyclase,which leads to eventual phosphorylation of other cellular enzymes.
C) The complex of protein hormone/receptor diffuses into the cell nucleus and has a suppressing effect on RNA synthesis.
D) All protein hormones are bound to a transport protein to move through the circulation.

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B

Binding to a receptor at the outer cell membrane to induce phosphorylation via adenylyl cyclase and cAMP of certain intracellular enzymes is a property of which class of hormone?


A) Protein
B) Steroid
C) Amino acid-derived
D) Both a and c

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Which one of the following statements concerning steroid hormones is correct?


A) Steroid hormones attach to a receptor on the surface of a cell,which eventually induces enzyme phosphorylation within the cell.
B) Steroid hormones are hydrophobic when free and bind to intracellular receptors in the nucleus.
C) Steroid hormones,because of their structure,are not bound to carrier proteins as they circulate in the blood.
D) Steroid hormones have a very short half-life (usually <30 minutes) in the circulation.

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Calcium concentration in the blood is regulated by which of the following hormones?


A) Calcitriol
B) Parathyroid hormone
C) Cortisol
D) Both a and b

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As part of homeostatic control by hormones,the metabolism of electrolytes and water balance is controlled in part by the renal system.What hormone synthesized by the kidneys affects water and electrolyte balance?


A) Aldosterone
B) Renin
C) Vasopressin; antidiuretic hormone (ADH)
D) Insulin

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Which of the following is an effect of increased parathyroid hormone (PTH) secretion from the parathyroid gland in the homeostatic control of serum calcium?


A) Decreased blood calcium levels
B) Increased renal absorption of phosphate
C) Decreased bone calcium efflux from the skeleton
D) Increased intestinal absorption of calcium

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D

Which of the following protein hormones produces a decrease in blood glucose by causing glucose to enter cells for energy production?


A) Insulin
B) Aldosterone
C) Thyroid hormone
D) Cortisol

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The half-life of a protein hormone in plasma is:


A) long,usually greater than 90 minutes.
B) long,at least 24 hours.
C) short,more than 1 hour but less than 3 hours.
D) short,approximately 10 to 30 minutes.

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Which one of the following hormones requires a transport protein to move it through the circulation?


A) Prolactin
B) Aldosterone
C) Estrogen
D) Parathyroid hormone

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The release of thyroid-stimulating hormone (from the pituitary gland) stimulates the release of thyroid hormones from the thyroid gland.When the level of thyroid hormones increases in the circulation,they shut off the release of TSH from the pituitary.This is an example of which type of feedback?


A) Open loop feedback
B) Positive feedback
C) Negative feedback
D) None of the above

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A group of hormones produced by the gastrointestinal tract that stimulates insulin secretion from the pancreas and slows the rate of gastric emptying is referred to as:


A) incretins.
B) insulinomas.
C) calcitriols.
D) steroids.

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